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09 Jan 2021 13:18 - 10 Jan 2021 10:28 #388204
by ketchim
mRNA vaccines work by providing the genetic code for our cells to produce viral proteins.
Once the proteins, which don’t cause disease, are produced,
the body launches an immune response against the virus
enabling the person to develop immunity !
Last edit: 10 Jan 2021 10:28 by
ketchim.
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09 Jan 2021 13:19 - 10 Jan 2021 10:29 #388205
by ketchim
Long before Moderna’s and Pfizer’s COVID-19 shots, scientists had been considering the use of :
genetically encoded vaccines in the fight against infectious diseases, cancer, and more
Last edit: 10 Jan 2021 10:29 by
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09 Jan 2021 13:20 - 10 Jan 2021 10:30 #388206
by ketchim
NO vaccines using this technology have made it this far in clinical trials.
Last edit: 10 Jan 2021 10:30 by
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09 Jan 2021 13:22 - 09 Jan 2021 16:15 #388207
by ketchim
mRNA can theoretically be used to produce any protein
with the upside that it much simpler to manufacture than the proteins themselves !
Last edit: 09 Jan 2021 16:15 by
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09 Jan 2021 13:25 - 10 Jan 2021 10:35 #388208
by ketchim
The success of the SARS-CoV-2 vaccines
“is really good for the RNA field
, because until very recently
there were just a handful of people
who really believed in mRNA vaccines,”
The Scientist.
Last edit: 10 Jan 2021 10:35 by
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09 Jan 2021 13:26 - 10 Jan 2021 16:16 #388209
by ketchim
A pair of scientists at the University of Pennsylvania, Katalin Karikó and Drew Weissman :
discovered that by altering the building blocks of RNA—nucleosides
—
they could address some of key limitations of the technique.
In a seminal 2005 paper, they reported that modified, synthetic nucleosides could both increase
protein production from the mRNA :
and drastically suppress the immune system’s reaction to the mRNA molecules themselves.
(Karikó is now a senior vice president at BioNTech, inventors of the Pfizer vaccine.)
Last edit: 10 Jan 2021 16:16 by
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09 Jan 2021 13:30 - 10 Jan 2021 10:41 #388210
by ketchim
Mapoui and his LINKS keeps arguing, albeit in Ignorance
about Old time Vaccines and continue like a DOG
refusing to Let GO : of an Old, OUTDATED ..dry, BONE
Last edit: 10 Jan 2021 10:41 by
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09 Jan 2021 13:36 - 10 Jan 2021 10:46 #388211
by ketchim
www.nature.com/articles/nrd.2017.243
mRNA vaccines — a new era in Vaccinology !
mRNA vaccines represent a promising
alternative to conventional vaccine approaches
because of
their high potency, capacity for rapid development
and potential for low-cost manufacture and safe administration ~
Last edit: 10 Jan 2021 10:46 by
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09 Jan 2021 13:44 #388212
by ketchim
Over the past decade, major technological innovation and research investment have enabled mRNA
to become a promising therapeutic tool in the fields of vaccine development and protein replacement therapy.
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