Now you are referencing the theories of Geert Vanden Bossche. Bossche writes articles for the OMICS group, which has been called “predatory” and was sued by the Federal Trade Commission for deceptive practices. And of course, once again, the website you're linking is run by libertarians. You seem incapable of understanding why this is.
Regardless, the errors of his paper, and Bossche's unfamiliarity with basic science, are addressed here:
www.deplatformdisease.com/blog/addressin...nden-bossches-claims
www.snopes.com/news/2021/03/26/geert-vanden-bossche/
www.mcgill.ca/oss/article/covid-19-criti...geert-vanden-bossche
Your allegory about "weed killers" is not quite relevant, and ignores the modular nature of vaccines; current technology allows for rapid reformulation and adjustment as necessary, allowing us to produce vaccines specific to problematic mutations. The idea that "you shouldn't vaccinate because it causes mutations" also runs counter to successful policies for responding to outbreaks (e.g. measles, mumps, meningococcal disease, etc).
And the evidence shows the opposite of what Bossche claims; we see hallmarks of memory responses induced by these vaccines from even a single dose, meaning that even though there is a drop in neutralization, it does not mean a loss in protection. Novavax’s recent Phase 3 clinical trial did show reduced efficacy against one variant, however the key point is that no one in this vaccinated group developed severe disease. This is because there is no significant change to the T cell response with the variants in either recovered or vaccinated individuals and T cell responses are critical determinants of patient clinical course. Also, evidence has already confirmed that antibodies cross-neutralize with ancestral variants. So "old" vaccines protect against old variants, and slowly, over time, protect against new ones.