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WASHINGTON/TAMPA (Reuters) - The U.S. State Department and Democratic presidential candidate Hillary Clinton on Tuesday stressed the need for ties with the Philippines to be based on mutual respect, after Manila's new leader raised worries about the future of the key alliance by calling President Barack Obama a "son of a bitch."

Despite U.S. dismay over Duterte's remarks, though, current and former U.S. officials played down the impact, saying they did not expect any serious damage to ties at a time of high tensions over China's extensive territorial claims in Asia.

The State Department said a planned first meeting between Obama and his counterpart Rodrigo Duterte on the sidelines of a regional summit in Laos on Tuesday was canceled because the tone of the Philippine leader's rhetoric raised questions about the chances of productive talks.